Manisha Koirala has last acted in a Tamil film Mumbai Express way back in 2005. After this she never acted in Tamil films again. She acted in Telugu and Bengali films though.

She is donning the role of Dhanush's mother-in-law in the remake of Rajni starrer Maapillai after a long gap, . She is also donning the role of Nayanthara's mother in the Malayalam film Electra.

While sharing her thoughts on this film, she said "I am getting married soon. I will continue to act in films even after marriage if I get good stories. People are commenting about me playing the role of a mother to Nayanthara in the film Electra.

The director of the film Shyam Prasad is a talented person. I have accepted this role because of the respect I have for him. There is nothing wrong in it. My character has significance. If the director is good I don't mind doing any kind of roles.

Acting as Dhanush's mother-in-law in the film Maapillai was an unforgettable experience. I am the vamp in this film. In real I am not that kind of a person. I like the role very much as it is unlike me."