The film, which features John Abraham, Shruti Haasan, Anil Kapoor, Naseeruddin Shah, Nana Patekar, Paresh Rawal and Dimple Kapadia, minted Rs 14.35 crore on its opening day, said a source from the production house.
'Welcome Back', which did not have any other big films clashing at the box office, is expected to have a good week.
The sequel to the 2007 film is the comeback film for actor Shiney Ahuja, who faded into obscurity after he was accused of rape by his former domestic help and was last seen on the silver screen in 2012.
Shiney is seen essaying the "spoilt" son of Naseeruddin, who plays a blind don named Wanted Bhai in the film.
