The 'Hindi Medium' star, who is undergoing treatment for a neuroendocrine tumour, a rare form of cancer, updated the display picture of his Twitter account.
He can be seen in a yellow T-shirt standing next to a glass door with earphones around his neck and is all smiles.
Khan left fans, friends, and colleagues in shock by opening up about his illness in March this year.
The National Award-winning actor tweeted about his illness, writing, "The unexpected makes us grow, which is what the past few days have been about."
On the work front, Irrfan will next be seen in 'Karwaan', which revolves around three oddballs from different walks of life who are thrown together on a somewhat bizarre journey which helps them find normalcy in their lives.
The movie is slated to release on August 3.