Every day brings with it many situations. Each situation brings with it some choices. Each choice brings with it two roads. One road which you run towards The other which you run away from. But RUN you must!

Such a situation arises for Siddharth (Abhishek Bachchan), where this run assumes significance like never before. Leaving behind his cocoon in Agra he reaches Delhi hoping to turn hid aspirations into reality.

Here he meets the beautiful Jhanavi (Bhoomika Chawla) whose innocence takes his breath away. But little does he know that she carries with her an excess baggage that threatens to take his life away.

This excess baggage is Jhanavi's demonic brother Ganpat Chowdhary (Mahesh Manjerekar) whose possessiveness of his sister spells pure poison.

The hand that dares to touch Jhanavi's heart just has to be cut. But Siddharth is the owner of awe-inspiring might that is hard to ignore. And thus begins a racy battle of one-up man ship between the two equally motivated men. Both of whom are used to getting what they want. Anytime. Every time. No matter what...!

Ganpat leaves no stones unturned to make life hell for Siddharth. Finally something fateful happens and Siddharth devises a foolproof way to combat devious Ganpat. A way that has no parallel! It is the unique way that will make Siddharth's Run a victorious one. And true victory is attained only when the Run ends...

Ayesha Jhulka makes a comeback after a long hiatus and plays Shivani, Siddharth's loving sister. The film also features Mukesh Rishi and Vijay Raaz in important roles. Music of the film is composed by Himesh Reshmmiya.

Run in a remake of a Tamil film of the same name which featured Madhvan and Meera Jasmine in lead roles.