"Off to Goa for IFFI - International Film Fest Of India, hosting the opening ceremony," Tisca posted on micro-blogging site Twitter.
Actor Rahul Khanna will co-host the opening ceremony with her.
The festival, which will take place at Ravindra Bhavan auditorium in Margao, aims to be a one-stop-shop for cultural exchanges between Indian filmmakers and artists and cinema experts from several countries.
Bollywood superstar Shah Rukh Khan will inaugurate the festival.
The guest list of the festival includes eminent French filmmaker Luc Besson, Hollywood actress Michelle Yeoh as well as Laurence Kardish, Dan Wolman, Raima Sen, Dino Morea and Prem Chopra.