"I don't understand 3D and don't enjoy it, but my son does. So, maybe for the larger portion of audiences, one should consider it for sequel," Saif told reporters.
"I didn't consider going for it this time. There was some talk earlier though. If it becomes a big action movie, then it is a good idea to shoot it in 3D," he added.
"Agent Vinod" is directed by Sriram Raghavan, and also features Saif's real life lady love Kareena Kapoor.
Saif says if at all a sequel takes shape, the character of Vinod will be staple.
"It will be the same Vinod with another cast for the sequels if at all it comes. It is too early to discuss right now," the 41-year-old said.
"Agent Vinod" hit screens Friday.