He is the middle son of Bollywood actor and politician Vinod Khanna, and the younger brother of actor Rahul Khanna.
Khanna made his acting debut in Bollywood in 1997 with the film 'Himalay Putra', but it was not successful at the box office.
He got his first box-office hit by doing J. P. Dutta directed 'Border' in the same year and bagged the Filmfare Best Debut Award.
Some of his films are Taal, Dil Chahta Hai,Humraaz, Hungama, LOC Kargil, Hulchul, Naqaab, Gandhi, My Father, Race, Mere Baap Pehle Aap, Aakrosh and many more.
He won Filmfare Award for Best Supporting Actor in 2002 for 'Dil Chahta Hai', Filmfare Award for Best Performance in a Negative Role for 'Humraaz', Screen Awards for Best Villain in 2009 for 'Race' and others.
His recent release was Rumi Jaffrey's 'Gali Gali Chor Hai'.