"Some sections of the press reported 'Department' is based upon real life characters in Mumbai police...it's not true, " the 50-year -old tweeted.
It was reported that the movie revolves around the Anti-Terrorist Squad created to eliminate the mafia and talks about the struggle within the police department.
The film stars Amitabh Bachchan as gangster called Sarjerao Gaikwad, southern star Rana Daggubati features as a grungy policeman and Sanjay Dutt will be seen in a pivotal role.
"Department" is set for May 18 release.