Released Friday, the film, co-produced by Nadiadwala Grandson Entertainment, grossed Rs.57 crore in India and Rs.15 crore overseas so far.
"Despite releasing during the IPL cricket frenzy, 'Housefull 2' has opened well in theatres across India. With its strong weekend performance, we believe 'Housefull 2' has also lived up to its name like predecessor," Nandu Ahuja, senior vice president, India Theatrical, Eros International Media Ltd, said in a statement.
Sajid Khan's last two directorial ventures - "Heyy Babyy" and "Housefull" - were huge hits.
A sequel to 2010 release "Housefull", the film's cast is called dirty dozen that comprises of Akshay Kumar, John Abraham, Riteish Deshmukh, Shreyas Talpade, Asin Thottumkal, Jacqueline Fernandez, Zarine Khan and Shahzan Padamsee. It also features veteran actors Mithun Chakraborty, Randhir Kapoor, Rishi Kapoor and Boman Irani.