Shruti pulled out of the project citing dates issue.
"After Shruti walked out of the project, the makers approached Tamannaah, and she's almost confirmed. The official confirmation should be out very soon," a source from the film's unit said.
Shruti, who is currently busy with four projects in her kitty, was paired with Karthi in the movie.
On Friday, the makers sent a legal notice to Shruti for exiting from the project.
If Tamannaah comes on board, it will be her third project with Karthi after Tamil actioner `Paiyya` and "Siruthai".
Being directed by Vamsi Paidipally, the film is set to be the remake of French drama "The Intouchables".
According to sources, Nagarjuna is essaying the role of a patient, and Karthi as his caretaker.
Meanwhile, Tamannaah will soon starting shooting for Telugu project "Bengal Tiger" with Ravi Teja.