The actress is expecting her second baby, due just two weeks after the Hollywood ceremony.
She says she's determined to attended the event after being nominated for the best supporting actress award for her role in Chicago.
According to The Sun, organisers have arranged for an ambulance to be parked outside the ceremony at the Kodak Theatre in Los Angeles.
Zeta Jones has been given an aisle seat near an exit, and a nurse and a doctor will keep an eye on her.
She is expected to have her baby at the exclusive Cedars Sinai hospital, where her son Dylan was born.