Reports suggested that Mani is planning to cast the duo for his new love story.
"No folks.. As much as I would love to... No film with Mani sir and Vidya Balan in the offering. unfortunately, " he wrote on his Twitter page.
Vidya and Madhavan's chemistry was much talked about after they sizzled on screen in Ratnam's "Guru" and later they created the same magic in a series of television commercials for Airtel.