The 'Born This Way' singer had sex for the first time when she was a teenager but admits she wasn't fully prepared so didn't enjoy it.
She said: 'I didn't lose my virginity until I was 17. But I have to say even then I wasn't ready and it was an absolutely terrible experience.
'It wasn't good at all. I have never not had safe sex, I have always asked a guy to be tested and to use protection, which was always my rule. Otherwise you're playing Russian Roulette.'
The 24-year-old hit maker said 'Sex is the ultimate expression of vulnerability and for me it was important to know that it was a proper relationship so it was sex as a source of love and nothing else.'
In the past, Gaga has claimed she is bisexual as well as saying she believes if you have sex with people you are not love with they will ruin your 'energy'.
She said: 'I have weird superstitions about sex. If you're not having sex with someone who really loves you they can screw up your energy.'