Justin Chambers' last onscreen appearance in `Grey's Anatomy` was back in November 2019, but his longtime character Alex Karev will officially get his sendoff in the March 5 episode.

A trailer for the episode entitled `Leave A Light On` (which you can watch above) flashes back through Chambers' 15 seasons on the show, seeing his character Alex start as a surgical intern but eventually rise through the ranks. `We're saying goodbye to Dr. Alex Karev,` title cards in the trailer read. `See how his story ends.`

Over the course of the episodes from Chambers' last appearance, through the surprise announcement of his exit, to `Leave A Light On,` the writers' room slowly left seeds that lead to the eventual answers to be revealed on March 5.

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Closure is coming. 💔#GreysAnatomy is set to reveal what happened to Justin Chambers' Alex Karev in an upcoming episode. Everything you need to know at the link in bio.

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Alex's onscreen wife Jo (Camilla Luddington) dropped hints that things weren't good with her husband - he wasn't returning her calls, for example - and at one point commented that if she didn't know him better, she would think he was pulling away from her to pay her back for pulling away from him a year earlier. Then, Jo

`It's a bit of a mystery [what's going on with Alex],` Vernoff said. `We don't watch Jo in the same place that we watched her in last season. We did it as carefully as we could. But it takes a while to get there.`