Set against the backdrop of the shaahiLucknow, Maddam Sirfeatures fourdynamic police officers Haseena Mallik (Gulki Joshi), Karishma Singh(Yukti Kapoor), Santosh Sharma (Bhavika Sharma) and Pushpa Singh (SonaliNaik) as they try solving cases that come in AminabadMahila Police Thana, in their unique yet powerful ways.
Haseena Mallik, the S.H.O (Station House Officer), is a young and a head-strong woman, who believes in bringing sensitivity in the manner of her policing. Whereas, Inspector Karishma Singh doesnot believe in emotional policing andis always ready to take the fierce way towards solving a case. While the two try to accommodate each other's clashing personalities and beliefs, the new recruit, Santosh Sharma tries to find a role model in them, often left confused.
Pushpa Singh is the Head Constable, the most experienced officer of the team and also Karishma's mother-in-law. While at work, the duo keeps it professional, at home the dynamics change as Pushpa becomes more authoritative. Her only wish now is to crack a big case before her retirement. Another interesting character is that of a news reporter, Sunny, played by Gaurav Wadhwa.A street-smart guy, he knows how to get his work done and get information from Maddam Sir's team.