The mishap apparently occurred Wednesday when Khan had to lift and throw a bulky man weighing about 100 kilos, but the actor unfortunately pulled a hamstring muscle.
Directed by A.R. Murugadoss, "Ghajini" is a remake of a Tamil film by the same name. Actress Asin stars opposite Khan in the action-packed film whose theme revolves around revenge.
Actors Surya and Jyothika had acted in the Tamil original.