With Madhuri being married off to US, the vetran painter M.F.Hussain had a hard time finding his new muse but he found her at last in Tabu, who according to him is a perfect embodiment of a modern woman.

Meenaxi is a joint effort of Hussain and his son Owais Husain.

Nawab (Raghvir Yadav), a popular novelist of Hyderabad, is suffering from the classic case of a writer's block. Five years have elapsed. Stories of substance seem to have dried up.

Almost providentially, Nawab comes across Meenaxi (Tabu) at a traditional qawwali ceremony. The young woman is enigmatic and individualistic. She's not quite willing to perform the part of a passive muse.

Meenaxi assumes different personae. She can be the mysterious perfume trader of Hyderabad, the exotic desert bloom of Jaisalmer and the orphaned Maria of Prague.

Inexorably, she consolidates her command over the novelist. She dismisses his renewed attempts at writing as insubstantial and hackneyed, plunging him into a state of deeper despair. She is scathingly critical about his story and is amused by one of the characters he creates, the lovelorn and awkward Kaameshwar.

Nawab strives to start on a new page all over again. Meenaxi comments that perhaps the book is in vain. In any case, it is much too late. The writer must survive and live, if he can, without her support, inspiration and criticism.

Delving into the limitless world of creative endeavor and the vicissitudes in the way of such endeavors, Meenaxi: Tale of 3 Cities approaches myriad aspects, the relationship between art, the real and the imagined being just one of them.

Meenaxi brings some of the most reknowned name like A.R.Rehman, Santosh Sivan, Sreekar Prasad, Sharmishta Roy, together on one platforum. The film is produced under the banner of Husain's home production 'Culture of the Streets Films'.