Chopra, the maker of several blockbusters in his chequered career, will be honoured at the festival, which offers a bouquet of 98 films from across 46 countries. Oscar winner Morgan Freeman and Egyptian actor Adel Imam would also woo fans at the event.
The seven-day festival - aimed at bridging cultural gaps between the East and West - will be held between December 11 - 17 and will screen Assamese director Jahnu Barua's Hindi film Maine Gandhi Ko Nahin Mara.
The section, which has six films, will also screen Reflections, an eight-minute silent film directed by Bejoy Nambiar starring Mohanlal, the award-winning Malayalam actor.
The other Indian entry in this section is an Indo-French produced Bengali feature Nisshabd.
Unlike DIFF 2004, which had a strong Bollywood quotient, this year the focus is more on quality cinema under a broader segment, cinema from the subcontinent.
The selection of films is across the board, with the objective of "using cinema from around the world to bring people together," DIFF director Neil Stephenson told scribes.
The Tale of an Indian Temple Dancer: Sringaram, directed by Sharada Ramanathan, will be premiered in the world section along with five other films including a war documentary Kosovo: The hand of Friendship.
Indian actors John Abraham and Lisa Ray will be part of a charity gala with its proceeds earmarked for Nelson Mandela Foundation.