The 72-year-old took to micro-blogging website Twitter to share an update.
"The start of another mission - the awareness for Hepatitis B... meeting authorities to take this forward - like Polio & TB," shared the 72-year-old, who flew to the capital earlier Monday.
Big B had previously tweeted about Hepatitis B virus (HBV).
The "Don" star has been associated with Unicef as a Global Ambassador for polio eradication since 2005. His active campaigning for the cause, coupled with other factors, led to India's polio-free status.
Now he is putting his weight behind the Hepatitis B campaign.
"Wish to start a campaign on awareness of Hepatitis B... Met some committed doctors and shall strategies... Detect and cured asap!," Big B had tweeted in December 2014.